Monday Night Football: 49ers vs Cardinals Handicapping Tips

San Francisco 49ers: A victory opens two-game lead

San Francisco enters this NFC West battle with a 5-2 record, which is good for a one-game lead in the NFC West. The Niners need this win to retain sole possession of first in the division and build momentum for the second half of the season. With Seattle losing on Sunday, a win moves SF two games up in the West. The 49ers frightening front seven will pose a major problem for a suddenly reeling Cardinals crew tonight.

Arizona Cardinals: Desperately need a win after three straight loses

Arizona desperately needs a win to keep pace in the NFC West division race. The Cards started the season at 4-0 but have lost three straight games and their quarterback situation is in flux. Following a preseason QB controversy, the Red Birds opened the season with John Skelton but he went down with an ankle injury and was replaced by Kevin Kolb in Week 1. Now Kolb has rib/chest injuries and Skelton is back under center.

Despite the recent losing streak by the Cards, this is still a very intriguing game because of the divisional implications that come with it. Top online sportsbooks like the one located at Sportsinteraction.com have the 49ers as -7.5 (-105) favorites to upend the host Cardinals in this contest. Skelton could be running for his life tonight. We will lay the point spread and back the Niners on the grand stage that is Monday Night Football.

Category : Sports News

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